Pharmaceutical Biotechnology

Data

Official data in SubjectManager for the following academic year: 2023-2024

Course director

Number of hours/semester

lectures: 28 hours

practices: 14 hours

seminars: 14 hours

total of: 56 hours

Subject data

  • Code of subject: OBA-115-T
  • 4 kredit
  • Biotechnology MSc
  • Basic modul
  • spring
Prerequisites:

OBA-128-T parallel

Exam course:

yes

Course headcount limitations

min. 1 – max. 50

Topic

Pharmaceutical biotechnology

Lectures

  • 1. Pharmaceuticals, biologics and biopharmaceuticals - Dr. Pongrácz Judit Erzsébet
  • 2. Plant biotechnology II. - Dr. Pongrácz Judit Erzsébet
  • 3. Cancer drugs using anti-cancer plant metabolites I. - Dr. Pongrácz Judit Erzsébet
  • 4. Cancer drugs using anti-cancer plant metabolites II. - Dr. Pongrácz Judit Erzsébet
  • 5. Cancer drugs - a different approach: appearance of monoclonal antibodies I. - Dr. Pongrácz Judit Erzsébet
  • 6. Cancer drugs - a different approach: monoclonal antibodies II. - Dr. Pongrácz Judit Erzsébet
  • 7. Cancer drugs - CAR-T cell therapy I. - Dr. Pongrácz Judit Erzsébet
  • 8. Cancer drugs - CAR-T cell therapy II. - Dr. Pongrácz Judit Erzsébet
  • 9. Drug development against viruses - the role of biotechnology I. - Dr. Pongrácz Judit Erzsébet
  • 10. Drug development against viruses - the role of biotechnology II. - Dr. Pongrácz Judit Erzsébet
  • 11. Drug development and biotechnology against bacterial infections I. - Dr. Pongrácz Judit Erzsébet
  • 12. Drug development and biotechnology against bacterial infections II. - Dr. Pongrácz Judit Erzsébet
  • 13. Mid-term test - Dr. Pongrácz Judit Erzsébet
  • 14. Mid-term test - Dr. Pongrácz Judit Erzsébet
  • 15. Cytokines and other simple peptides and proteins – the easiest task for pharmaceutical biotechnologiests? I. - Dr. Pongrácz Judit Erzsébet
  • 16. Cytokines and other simple peptides and proteins – the easiest task for pharmaceutical biotechnologiests? II. - Dr. Pongrácz Judit Erzsébet
  • 17. (L)ADMETOX I. - Dr. Pongrácz Judit Erzsébet
  • 18. (L)ADMETOX II. - Dr. Pongrácz Judit Erzsébet
  • 19. Factors influencing drug response I. - Dr. Pongrácz Judit Erzsébet
  • 20. Factors influencing drug response II. - Dr. Pongrácz Judit Erzsébet
  • 21. Molecular drug transport I. - Dr. Pongrácz Judit Erzsébet
  • 22. Molecular drug transport II. - Dr. Pongrácz Judit Erzsébet
  • 23. Influencing drug transporters I. - Dr. Pongrácz Judit Erzsébet
  • 24. Influencing drug transporters II. - Dr. Pongrácz Judit Erzsébet
  • 25. Test systems for toxicology I. - Dr. Pongrácz Judit Erzsébet
  • 26. Test systems for toxicology II. - Dr. Pongrácz Judit Erzsébet
  • 27. Test systems for drug efficacy I. - Dr. Pongrácz Judit Erzsébet
  • 28. Test systems for drug efficacy II. - Dr. Pongrácz Judit Erzsébet

Practices

  • 1. Principals of gene cloning - using the NCBI database
  • 2. Cloning a specific gene - a practical approach 1
  • 3. Cloning a specific gene - a practical approach 2
  • 4. Cloning a specific gene - a practical approach 3
  • 5. Culturing organisms for protein production
  • 6. Culturing organisms for protein production
  • 7. Selection and application of organisms for protein production
  • 8. Protein purification for therapeutic application 1
  • 9. Protein purification for therapeutic application 2
  • 10. Technical approach for monoclonal antibody production 1
  • 11. Technical approach for monoclonal antibody production 2
  • 12. Testing toxicity using methodology of biotechnology
  • 13. Efficacy testing using methodology of biotechnology
  • 14. Nanotechnological methods

Seminars

  • 1. Pharmaceuticals, biologics and biopharmaceuticals
  • 2. Cancer drugs using anti-cancer plant metabolites I.
  • 3. Cancer drugs - a different approach: appearance of monoclonal antibodies I.
  • 4. Cancer drugs - CAR-T cell therapy I.
  • 5. Drug development against viruses - the role of biotechnology I.
  • 6. Drug development and biotechnology against bacterial infections I.
  • 7. Mid-term test
  • 8. Cytokines and other simple peptides and proteins – the easiest task for pharmaceutical biotechnologiests? I.
  • 9. (L)ADMETOX I.
  • 10. Factors influencing drug response I.
  • 11. Molecular drug transport I.
  • 12. Influencing drug transporters I.
  • 13. Test systems for toxicology I.
  • 14. Test systems for drug efficacy I.

Reading material

Obligatory literature

Literature developed by the Department

Lecture ppt

Notes

Recommended literature

Pharmaceutical biotechnology, Ed: Gary Walsh, Wiley

Conditions for acceptance of the semester

Maximum of 25 % absence allowed

Mid-term exams

Written test

Making up for missed classes

None

Exam topics/questions

meetstreet, Teams, Moodle

Examiners

  • Bóvári-Biri Judit
  • Dr. Pongrácz Judit Erzsébet

Instructor / tutor of practices and seminars

  • Ádám Zoltán Mihály
  • Bóvári-Biri Judit