Pharmaceutical Applied Immunology

Adatok

A Tantárgybejelentőben megadott hivatalos adatok az alábbi tanévre: 2023-2024

Tematika

Pharmacist perspective on pharmaceutical products that affect the immune system or function in an immunological manner. The course describes the immunological effect and mechanism of action for various pharmaceutical products (both conventional small molecules and modern macromolecules) with special attention to drugs with direct immune-modulation or sharing common immunological side-effects. The course details which products and drug combinations lead to efficient immune-mediated disease resolution or the development of adverse side-effects due to affecting the immune system. The course also discusses the way drug combinations affect the immune system.

Előadások

• 1. Pharmaceutical products acting on the immune system from a pharmacist perspectiv, course structure, obligations - Dr. Kvell Krisztián
• 2. Production of antibody-based products, identification of their products - Dr. Kvell Krisztián
• 3. Modification of antibody-based products – fusion, labeling, radioactive and toxic antibodies - Dr. Kvell Krisztián
• 4. Utilization of monoclonal antibodies in cancer therapy – products acting directly on cancer cells or the tumor micro-environment - Dr. Kvell Krisztián
• 5. Modulation of the immune response through monoclonal antibodies in autoimmune inflammatory diseases - Dr. Kvell Krisztián
• 6. Production of pharmaceutically relevant cytokines, chemokines and their receptors - Dr. Kvell Krisztián
• 7. Modulation of immune response in malignant diseases through the use of cytokines - Dr. Kvell Krisztián
• 8. Modulation of immune response in autoimmune diseases through the use of cytokines - Dr. Kvell Krisztián
• 9. The effect of non-steroid anti-inflammatory drugs on immune cells and molecular processes - Dr. Kvell Krisztián
• 10. The effect of steroid anti-inflammatory drugs on immune cells and molecular processes - Dr. Kvell Krisztián
• 11. The effect of cytostatic drugs on immune cells and molecular processes - Dr. Kvell Krisztián
• 12. The effect of various conventional and modern vaccines on immune cells - Dr. Kvell Krisztián
• 13. The role of certain vitamins (B, C, D, E) in the prevention and therapy of immune-pathologies - Dr. Kvell Krisztián
• 14. The role of certain trace elements (copper, zinc, selenium) in the prevention and therapy of immune-pathologies - Dr. Kvell Krisztián

Gyakorlatok

Szemináriumok

• 1. Quick-test: Covid test
• 2. Quick-test: pregnancy test
• 3. Immunoglobulin therapy: IVIG collection, donor validation, pooling
• 4. Immunoglobulin therapy: IVIG application in certain diseases
• 5. Determination of blood groups with various methods
• 6. Hemopoietic drugs: mechanism of action, application
• 7. Midterm consultation seminar
• 8. Arthritis treatment using small molecule-based immune therapy (NSAID, steroid)
• 9. Arthritis treatment using macromolecule-based immune therapy (anti-IL6)
• 10. Arthritis treatment using small molecule-based immune therapy (5-ASA)
• 11. Arthritis treatment using macromolecule-based immune therapy (anti-TNFalpha)
• 12. Immune-checkpoint therapy (CTLA4, PD1), machanism of action, side effects
• 13. Immune-checkpoint therapy (CTLA4, PD1) in certain malignant diseases
• 14. Final consultation seminar

A tananyag elsajátításához szükséges segédanyagok

Kötelező irodalom

Saját oktatási anyag

Lecture and seminar ppt

Jegyzet

Lecture notes, learning materials of the lectures are available on MeetStreet, Moodle
Pharmaceutical Applied Immunology 2019

Ajánlott irodalom

A félév elfogadásának feltételei

Maximum of 25 % absence allowed

Félévközi ellenőrzések

Written test

Távolmaradás pótlásának lehetőségei

According to the Code of Studies and Examinations.

Vizsgakérdések

MeetStreet, Teams, Moodle

Vizsgáztatók

• Dr. Bánfai Krisztina
• Dr. Kvell Krisztián

Gyakorlatok, szemináriumok oktatói

• Bóvári-Biri Judit
• Dr. Bánfai Krisztina
• Dr. Kvell Krisztián